Biomarkers in Inflammatory Bowel Diseases

Zusatztext

Incorporates current biomarkers within practical algorithms that can be applied to clinical practice Addresses predictive (early or ultra early) biomarkers of response to current therapeutic agents which form the backbone of medical therapy as well as prognostic biomarkers which predict disease course in inflammatory bowel disease Presents the current state-of-the art in the research strategies that are being applied to biomarker discovery

Autorenportrait

The editors are currently reviewers of major international journals. They are experts in inflammatory bowel disease (IBD) each with an interest in developing biomarkers for research development and improving patient care. The editors have also developed strong reputations within the international IBD community and have connections with each of the nominated chapter contributors. Nik Sheng Ding is a committee member for the European Crohns and Colitis Organisation (ECCO) and a clinical lecturer at Imperial College, London. He has supervised students and is a member of the Computational Medicine division of the department of medicine. He is completing a PhD entitled Clinical and metabolic predictors of response to anti-TNF therapy in Crohns disease. He has authored and co-authored manuscripts, book chapters and has a major grant from ECCO to conduct his research. He is currently the principal investigator of an international study into access to IBD investigations (biomarkers) by health professionals, particularly investigating rates of usage according to health expenditure and quality of care for patients (Access to IBD investigations - ACCID). Nik has an interest in translational research with investigating the function of the microbiome through metabonomics and its relation to outcomes in IBD. Peter De Cruz MBBS, Ph.D, FRACP Peter De Cruz is Director of the IBD service at the Austin Hospital, Senior lecturer at the University of Melbourne and Life Fellow of Clare Hall at the University of Cambridge.  Peters doctoral research at The University of Melbourne identified the optimal strategy for preventing Crohns disease recurrence after resectional surgery. The findings of the research have been published in the Lancet and Gastroenterology and have changed practice internationally. His postdoctoral fellowship in complex IBD and clinical nutrition was undertaken between Addenbrookes Hospital, Cambridge and St Marks Hospital,London. Peters ongoing clinical research interests include identifying predictors of response to IBD therapeutics which he maintains through his translational research interest in molecular microbiology and immunology.

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