Advanced Chemical Biology

Zusatztext

<b>Advanced Chemical Biology</b><p><b>The modern approach to teaching chemical biology</b><p><i>Advanced Chemical Biology</i> is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections.<p>Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples of how the concept has been turned into practice. The subdivision of the contents into core and supplemental chapters enables a flexible use in teaching, both for a one-semester and a two-semester course.<p>Written by authors and editors coming from the leading scientific institutions that have developed the concepts and technologies for this discipline,<i>Advanced Chemical Biology</i> includes specific information on topics like:<ul><li>DNA function, synthesis and engineering, chemical approaches to genome integrity, and RNA function, synthesis, and probing</li><li>Chemical approaches to transcription and RNA regulation in vivo, chemical biology of genome engineering, and peptide/protein synthesis and engineering</li><li>Directed evolution for chemical biology, chemical biology of cellular metabolism, chemical biology of lipids, and protein post-translational modifications</li><li>Chemical glycobiology, chemical and enzymatic modification of proteins, genetic code expansion, bio-orthogonal chemistry, and cellular imaging</li></ul><p>With its broad scope and focus on turning concepts into applications,<i>Advanced Chemical Biology</i> is an excellent starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer.<p><b>With a Foreword by Nobel Laureate Carolyn Bertozzi.</b>

Autorenportrait

<p><b>Howard C. Hang,</b> PhD, Scripps Research, La Jolla, USA.</p><p><b>Matthew R. Pratt,</b> PhD, University of Southern California, Los Angeles, USA.</p><p><b>Jennifer A. Prescher,</b> PhD, University of California, Irvine, USA.</p>

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