Dendrites

Zusatztext

This book is dedicated towards highlighting the advances made in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of this crucial neuronal component. The book begins by presenting current knowledge about the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are discussed. Recent work describing how dendritic organization and connectivity are perturbed in disease are discussed. A unique aspect of the book is that diverse neuronal cell types across vertebrates and invertebrates are featured, enabling comparison of mechanisms across distinct circuits and species. The book comprises seven parts aimed to cover the major advances in the field: Part 1, Introduction to dendrites; Part 2, Basic biology of dendrites; Part 3, Patterning dendritic architecture of neurons and their populations; Part 4, Cellular and molecular control of dendrite development and maintenance; Part 5, Synapse formation onto dendrites; Part 6 Dendrites in disease and Part 7 Technical developments advancing the study of dendrites. This book will provide a good entry point for students interested in Neuroscience as well as for clinicians.

Autorenportrait

Kazuo Emoto: Professor, Department of Biological Sciences, The University of Tokyo, Japan Rachel Wong: Professor, Department of Structural Biology, University of Washington, USA Eric Huang: Professor, Department of Pathology, University of California San Francisco, USA Casper Hoogenraad: Professor, Department of Biology, Utrecht University, The Netherlands

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