Introduction of Coumarin

Zusatztext

The importance of Coumarin as anticoagulant dicoumarol by a number of species of fungi. This occurs as the result of the production of 4-hydroxycoumarin, then further (in the presence of naturally occurring formaldehyde) into the actual anticoagulant dicoumarol, a fermentation product and mycotoxin. Dicoumarol was responsible for the bleeding disease known historically as "sweet clover disease" in cattle eating moldy sweet clover silage.In basic research, preliminary evidence exists for coumarin having various biological activities, including anti-inflammatory, anti-tumor, antibacterial, and antifungal properties, among others.

Autorenportrait

The author Parin Shaikh holds masters in chemistry (Organic Chemistry) from Department of Chemistry, Sardar Patel University, VV Nagar, Anand. The author has been awarded Ph.D. for the thesis submitted by him entitled 'synthesis, characterization and antimicrobial screening of benzofuranyl styryl pyridine/ pyrazolyl pyrazoline coumarins"

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